Dihexa (5mg/capsule), 60 Capsules
$69.99
Dihexa capsules is an orally active, synthetic oligopeptide engineered for the investigation of synaptic plasticity and cellular repair. It functions as a potent agonist of the Hepatocyte Growth Factor (HGF) system. Research focuses on its ability to facilitate the formation of new functional synaptic connections and its high affinity for the c-Met receptor, making it a primary subject for studies on neuroregeneration and cognitive modeling
Dihexa is recognized in experimental pharmacology for its “picomolar” potency, suggesting it may be several orders of magnitude more effective than endogenous growth factors in promoting neuronal growth.
Key Areas of Laboratory Investigation:
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HGF/c-Met Pathway Modulation: Dihexa binds directly to HGF, enhancing its ability to activate the c-Met receptor. This signaling cascade is critical for cell survival, tissue regeneration, and the inhibition of apoptosis in neural tissues.
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Synaptogenesis & Spinogenesis: Laboratory studies utilize Dihexa to observe the growth of new dendritic spines and the strengthening of existing synaptic junctions. It is a vital tool in research concerning Traumatic Brain Injury (TBI) and age-related cognitive decline models.
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Blood-Brain Barrier (BBB) Permeability: Unlike many large-chain peptides, Dihexa’s small-molecule structure allows it to effectively cross the BBB. This makes the capsule format particularly useful for researchers studying systemic delivery and central nervous system (CNS) distribution.
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Protein-Protein Interaction: Dihexa is used in studies to examine how small molecules can stabilize or promote the dimerization of growth factors, providing insight into novel pathways for cellular signaling and repair.
Chemical & Technical Specifications
| Property | Specification |
| Chemical Name | N-hexanoic-Tyr-Ile-(6) aminohexanoic amide |
| Molecular Formula | $C_{27}H_{44}N_{4}O_{5}$ |
| Molecular Weight | 504.67 g/mol |
| Purity | ≥99% (HPLC Verified) |
| CAS Number | 1401708-83-5 |
| Format | Encapsulated Powder (Precise mg dosing) |
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