Dihexa – Powder, 500mg

$97.99

Dihexa Peptide is an orally active, blood-brain barrier (BBB) permeable oligopeptide derived from Angiotensin IV. It is engineered for investigation into synaptic plasticity and neuroregeneration. By acting as a potent agonist of the Hepatocyte Growth Factor (HGF) and its receptor, c-Met, Dihexa is studied for its potential to facilitate the formation of new functional synaptic connections in experimental models of neurological decline.

Description

The hallmark of Dihexa  peptide research is its “picomolar” potency. In comparative assays, Dihexa has demonstrated the ability to promote spinogenesis and synaptogenesis with efficacy that far exceeds endogenous growth factors.

Key Areas of Laboratory Investigation:

  • HGF/c-Met Pathway Activation: Dihexa Peptide binds with high affinity to HGF, facilitating its dimerization and subsequent activation of the c-Met receptor. This signaling cascade is a critical regulator of cell survival, migration, and tissue repair.

     

  • Synaptic Connectivity: Research indicates that Dihexa Peptide fosters the development of new neurons and reinforces existing synaptic junctions. Scientists use this compound to study the “re-wiring” of neural networks in models of Traumatic Brain Injury (TBI) and Alzheimer’s-like impairment.

     

  • Neuroprotective Resilience: Laboratory studies have explored Dihexa Peptide ability to protect neurons from apoptosis (programmed cell death) and reduce neuroinflammation by modulating pro-inflammatory cytokines like IL-1$\beta$ and TNF-$\alpha$.

     

  • Angiotensin IV Analogy: As an Angiotensin IV analog, Dihexa is utilized to explore the brain’s Renin-Angiotensin System (RAS) and its influence on spatial learning and memory consolidation.

     


Chemical & Technical Specifications

Property Specification
Chemical Name N-hexanoic-Tyr-Ile-(6) aminohexanoic amide
Molecular Formula $C_{27}H_{44}N_{4}O_{5}$
Molecular Weight 504.67 g/mol
Purity ≥99% (HPLC Verified)
CAS Number 1401708-83-5
Appearance White Lyophilized Powder
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