Sunifiram – powder, 10 grams

The High-Potency Ampakine: The Science of Sunifiram

Sunifiram (DM-235) is a synthetic, piperazine-derived research chemical that serves as a highly potent cognitive enhancer. While it is structurally related to the racetam family, it is distinguished by the breaking of the pyrrolidone backbone, categorizing it as an ampakine-like compound. In laboratory models, Sunifiram is noted for its extreme potency—often cited as being up to 1,000 times more active than Piracetam on a per-weight basis—making it a primary subject for research into neurodegenerative recovery and cognitive optimization.

Mechanism of Action:

Sunifiram operates primarily as an AMPA receptor modulator. It enhances glutamatergic neurotransmission by facilitating the activity of AMPA receptors, which are critical for fast synaptic transmission and Long-Term Potentiation (LTP)—the cellular basis for learning and memory. Additionally, research indicates that Sunifiram acts as a cholinergic, stimulating the release of acetylcholine in the cerebral cortex. It has also been shown to activate the CaMKII and PKC$\alpha$ pathways, which are essential for synaptic plasticity. This dual action on glutamate and acetylcholine systems provides a robust framework for studying improved mental clarity and memory consolidation.

Technical Specifications:

• Chemical Name: 1-benzoyl-4-propanoylpiperazine

• CAS Number: 314728-85-3

• Molecular Formula: $C_{14}H_{18}N_{2}O_{2}$

• Molecular Weight: $246.30 \, g/mol$

• Purity: >99% (HPLC Verified)

• Form: Oral Capsules / Research Powder

Applications in Human Research:

Sunifiram is highly valued in the research community for its rapid onset and high bioavailability:

• Memory Consolidation: Investigating the compound’s ability to prevent or reverse amnesia in experimental models, particularly regarding passive avoidance and spatial learning.

• Enhanced Focus and Alertness: Studies focus on Sunifiram’s role in increasing mental energy and concentration without the cardiovascular strain of traditional stimulants.

• Neurodegenerative Research: Analyzing the potential for Sunifiram to mitigate cognitive deficits associated with Alzheimer’s disease and other forms of age-related decline.

• Synaptic Plasticity: Researching how the activation of the glycine-binding site of NMDA receptors by Sunifiram influences neuronal communication and brain health.

The Swiss Chems Scientific Standard

When you look for Sunifiram for sale, the compound’s extreme potency requires absolute precision in dosing and purity. At Swiss Chems, we guarantee that our Sunifiram is strictly third-party lab tested via HPLC to ensure a minimum purity of 99%. Our manufacturing process ensures that every capsule contains the exact specified concentration, free from unreacted precursors or heavy metals.

Buy online today from the Official Swiss Chems website and secure the high-purity ampakines required for elite-level neurochemical and cognitive research.