Synephrine – Solution, 1500 mg (50 mg/1 ml)

Adrenergic Modulation: The Science of Synephrine

Liquid Synephrine is a naturally occurring protoalkaloid primarily found in the fruit of Citrus aurantium (bitter orange). Structurally related to endogenous catecholamines like epinephrine and norepinephrine, Synephrine serves as a potent research tool for investigating the autonomic nervous system. Unlike its banned predecessor, ephedrine, Synephrine is studied for its ability to enhance metabolic expenditure and lipolysis with significantly less impact on heart rate and blood pressure, making it a “cleaner” candidate for metabolic research.

Mechanism of Action:

Liquid Synephrine operates as a sympathomimetic amine, primarily binding to the $\beta$-3 adrenergic receptors located in adipose tissue. Activation of these receptors stimulates lipolysis (the breakdown of fats) and increases the basal metabolic rate (BMR). To a lesser extent, it interacts with $\alpha$-1 and $\alpha$-2 receptors, which are involved in vasoconstriction and glucose metabolism. Because of its specific affinity for $\beta$-3 receptors over $\beta$-1 or $\beta$-2 (which are predominant in heart tissue), researchers use Synephrine to study thermogenesis without the typical cardiovascular strain. The compound is metabolized in the liver via monoamine oxidase (MAO) and sulfation pathways.

Technical Specifications:

• Chemical Name: 4-[1-hydroxy-2-(methylamino)ethyl]phenol

• CAS Number: 94-07-5

• Molecular Formula: $C_{9}H_{13}NO_{2}$

• Molecular Weight: $167.21 \, g/mol$

• Purity: >99% (HPLC Verified)

• Concentration: 50mg/ml

• Form: Liquid Solution (30ml bottle)

Applications in Human Research:

Synephrine is a staple in clinical studies focused on energy homeostasis and performance:

• Fat Oxidation & Weight Management: Investigating the compound’s ability to increase the rate of fat oxidation during rest and moderate-intensity exercise.

• Basal Metabolic Rate (BMR): Researching the increase in energy expenditure (thermogenic effect) without the induction of central nervous system overstimulation.

• Exercise Performance: Studies focus on Synephrine’s role in improving stamina and muscular endurance by optimizing substrate utilization.

• Appetite Regulation: Analyzing the potential for adrenergic signaling to modulate satiety and caloric intake in metabolic syndrome models.

The Swiss Chems Scientific Standard

When you look for Liquid Synephrine for sale, the stability of the liquid formulation is vital for dosing precision. Many unverified liquid solutions suffer from precipitation or degradation. At Swiss Chems, our Synephrine liquid is formulated at 50mg/ml to ensure high solubility and consistent bioavailability across all research protocols. Each batch is third-party lab tested via HPLC to guarantee that the concentration matches the label exactly.

Buy online today from the Official Swiss Chems website and benefit from the stability and purity that rigorous metabolic research demands.