Synephrine HCl – Powder, 20 grams

Enhanced Bioavailability: The Science of Synephrine HCl

Synephrine HCl is the synthetic hydrochloride salt form of the naturally occurring protoalkaloid p-synephrine. In research applications, the “HCl” designation is critical; by converting the base molecule into a hydrophilic salt, researchers achieve significantly improved solubility and dissolution rates in aqueous environments. This makes Synephrine HCl a preferred candidate for precision-based studies where consistent bioavailability and rapid systemic absorption are required to accurately measure catecholamine-associated responses.

Mechanism of Action:

Synephrine HCl functions as a sympathomimetic agent with a high degree of tissue selectivity. It primarily acts as an agonist for $\beta$-3 adrenergic receptors, which are densely located in adipose tissue and are responsible for regulating thermogenesis and lipolysis. Unlike other stimulants, Synephrine HCl exhibits low affinity for $\beta$-1 and $\beta$-2 receptors (found in heart and lung tissue), allowing researchers to study increased energy expenditure while minimizing potential impacts on heart rate and blood pressure. The compound undergoes hepatic metabolism via monoamine oxidase (MAO) enzymatic degradation and sulfation, with metabolic clearance occurring primarily through the renal system.

Technical Specifications:

• Chemical Name: 4-[1-hydroxy-2-(methylamino)ethyl]phenol hydrochloride

• CAS Number: 5985-28-4

• Molecular Formula: $C_{9}H_{13}NO_{2} \cdot HCl$

• Molecular Weight: $203.66 \, g/mol$

• Purity: >99% (HPLC Verified)

• Form: Oral Capsules / Research Powder

Applications in Human Research:

The refined solubility of the HCl formulation makes it ideal for a variety of metabolic studies:

• Basal Metabolic Rate (BMR): Investigating the compound’s role in increasing resting energy expenditure through non-shivering thermogenesis.

• Lipid Metabolism: Researching the acceleration of fat breakdown (lipolysis) and the utilization of fatty acids as a primary fuel source during exercise.

• Catecholamine Signaling: Analyzing the interaction between synthetic phenylethanolamines and the autonomic nervous system.

• Appetite and Satiety: Studies focus on how adrenergic stimulation can modulate hunger signals and caloric intake in obesity research models.

The Swiss Chems Scientific Standard

When you look for Synephrine HCl for sale, the stability of the salt form is paramount to ensuring your data is not compromised by degradation. At Swiss Chems, we guarantee that our Synephrine HCl is strictly third-party lab tested to ensure the correct salt-to-base ratio and a minimum purity of 99%.

Our capsules are produced in a controlled environment to prevent moisture absorption, ensuring a shelf-stable product for your laboratory needs. Buy online today from the Official Swiss Chems website and secure the high-purity adrenergic agonists required for advanced metabolic research.