CJC-1295 with DAC, 2mg
CJC-1295 with DAC is a synthetic, 30-amino acid peptide analog of Growth Hormone Releasing Hormone (GHRH). Unlike the standard version, this molecule features a Drug Affinity Complex (DAC) modification, which significantly enhances its structural stability and extends its half-life in experimental conditions. It is a primary subject in studies involving sustained receptor affinity and the pulsatile release of signaling molecules.
The defining characteristic of this compound is the DAC modification, which allows the peptide to bind covalently to circulating albumin after administration in experimental models.
Key Areas of Laboratory Investigation:
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Extended Pharmacokinetics: The DAC modification allows for extended stability in solution and in vivo compared to the non-modified variant. This makes it particularly suitable for prolonged laboratory studies where frequent application is not feasible.
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Selective Receptor Affinity: In vitro studies demonstrate that CJC-1295 with DAC maintains high affinity for the GHRH receptors, stimulating the pituitary gland to observe the dynamics of growth hormone secretion.
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Biomimetic Signaling: Researchers utilize this compound to study how sustained GHRH receptor activation influences the “pulse” frequency and amplitude of growth hormone release in animal models.
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Metabolic Research: Investigations focus on how prolonged exposure to this analog affects lipid metabolism, protein synthesis, and cellular repair pathways over an extended timeframe.
Chemical & Technical Specifications
| Property | Specification |
| Sequence | Tyr-d-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Ile-Ser-Arg-Lys-(DAC) |
| Molecular Formula | $C_{152}H_{252}N_{44}O_{42}$ (approximate) |
| Modification | Drug Affinity Complex (DAC) |
| Purity | ≥99% (HPLC Verified) |
| Form | Lyophilized Powder |
| CAS Number | 863288-34-0 |
| Cjc-1295-with-dac-2mg |
Vial ,KIT (10 vials) |
|---|
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