GHK-Cu Copper Peptide
GHK-Cu peptide is a synthetic tripeptide-copper complex (Gly-His-Lys) engineered for research into extracellular matrix (ECM) stability and cellular regeneration. As a potent activator of tissue remodeling, it is studied for its ability to modulate the expression of genes involved in wound healing, antioxidant defense, and the synthesis of structural proteins like collagen and elastin.
GHK-Cu peptide functions as both a copper carrier and a signaling molecule. By facilitating the cellular uptake of copper, it supports the function of copper-dependent enzymes essential for tissue integrity.
Key Areas of Laboratory Investigation:
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Collagen & Elastin Modulation: GHK-Cu peptide is a primary subject in dermatological research. Studies focus on its ability to stimulate fibroblasts to increase the production of Type I and Type III collagen and glycosaminoglycans, enhancing the structural framework of the skin in vitro.
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Gene Expression & Epigenetics: Research indicates that GHK-Cu can influence the expression of over 4,000 human genes. It is investigated for its ability to “reset” genes to a more youthful state, particularly those linked to DNA repair and antioxidant activity.
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Wound Healing Signaling: Experimental models utilize GHK-Cu to observe the acceleration of tissue repair. It is studied for its role in chemoattraction (pulling repair cells to a site of injury) and the modulation of Metalloproteinases (MMPs) to prevent excessive scarring.
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Anti-Inflammatory & Antioxidant Effects: GHK-Cu peptide is examined for its ability to reduce pro-inflammatory cytokines such as IL-1 and TNF-$\alpha$. Additionally, it supports the activity of Superoxide Dismutase (SOD), providing a model for studying cellular protection against oxidative stress.
Chemical & Technical Specifications
| Property | Specification |
| Sequence | Glycyl-L-Histidyl-L-Lysine ($Cu^{2+}$) |
| Molecular Formula | $C_{14}H_{22}CuN_{6}O_{4}$ |
| Molecular Weight | 401.91 g/mol |
| Purity | ≥99% (HPLC Verified) |
| CAS Number | 89030-95-5 |
| Appearance | Distinctive Blue Crystalline Powder |
| GHK-Cu Copper Peptide |
10mg KIT (10 vials) ,50mg (1 vial) |
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